Letter: probiotics vs. lactulose for minimal hepatic encephalopathy therapy

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منابع مشابه

multistrain probiotics and lactulose in the treatment of minimal hepatic encephalopathy

background: some evidence has shown benefits of probiotics in the management of minimal hepatic encephalopathy (mhe). we evaluated the efficacy of a multistrain probiotic compound, alone and in combination with lactulose, in the treatment of mhe. materials and methods: h   is study has two parts. first, consecutive adult patients with mhe were randomized to receive lactulose (30–60 ml/day) + pr...

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Clinical efficacy and safety of lactulose for minimal hepatic encephalopathy: a meta-analysis.

OBJECTIVE To evaluate the clinical efficacy of lactulose in patients with minimal hepatic encephalopathy (MHE). METHODS Randomized controlled trials (RCTs) comparing lactulose with placebo or with no intervention in the management of MHE that were conducted from January 1990 to July 2011 were searched from MEDLINE, EMBASE, SCI, Cochrane Controlled Trials Register, and China Biological Medicin...

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Minimal Hepatic Encephalopathy (MHE)

1. Episodic (precipitant-induced) encephalopathy, commonly seen in the hospital setting, where a superimposed event is a key factor. 2. Persistent (chronic) encephalopathy, seen with extensive portal–systemic shunts and after portocaval shunt surgery or placement of transjugular intrahepatic portosystemic shunt (TIPS). 3. Minimal (subclinical) encephalopathy reflects alterations in cognitive fu...

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Minimal hepatic encephalopathy.

Minimal hepatic encephalopathy (MHE) is the mildest form of spectrum of hepatic encephalopathy (HE). Patients with MHE have no recognizable clinical symptoms of HE but have mild cognitive and psychomotor deficits. The prevalence of MHE is high in patients with cirrhosis of liver and varies between 30% and 84%; it is higher in patients with poor liver function. The diagnostic criteria for MHE ha...

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Minimal hepatic encephalopathy

Hepatic encephalopathy (HE) is a neuropsychiatric disorder that may accompany either acute or chronic liver disease. It is defined as a disturbance of central nervous system function due to hepatic insufficiency and includes a large spectrum of clinical manifestations such as decreased intellectual function, personality disorders, alterations in level of consciousness and neuromuscular dysfunct...

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ژورنال

عنوان ژورنال: Alimentary Pharmacology & Therapeutics

سال: 2014

ISSN: 0269-2813

DOI: 10.1111/apt.12661